Wednesday, November 10, 2010

Drinking, Smoking Up Early Alzheimer's










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Q. Glen, Does Drinking and Smoking have any effect on Memory?


A. Study Shows Cigarettes and Alcohol Lead to Earlier Development of Alzheimer's Disease

People who smoke a pack of cigarettes or more a day develop Alzheimer's disease years earlier than those who do not, and heavy drinking of alcohol increases the risk even more.
In what is being lauded as a significant finding, research presented at the American Academy of Neurology's 60th Anniversary Annual Meeting this week in Chicago shows that smoking and drinking are among the most important preventable risk factors for Alzheimer's disease.
Researcher Ranjan Duara, MD, of the Wien Center for Alzheimer's Disease at Mount Sinai Medical Center in Miami Beach, Fla., found that a combination of heavy drinking and heavy smoking leads to an earlier onset of Alzheimer's disease.
"It has been projected that a delay in the onset of the disease by 5 years would lead to a nearly 50% reduction in the total number of Alzheimer's cases," Duara says in a news release. "If we can reduce or eliminate heavy smoking and drinking, we could substantially delay the onset of Alzheimer's disease for people and reduce the number of people who have Alzheimer's at any point in time."
Duara's study involved 938 people aged 60 and older with possible or probable Alzheimer's. Family members provided information regarding the patients' alcohol consumption and cigarette usage.
Heavy smoking was defined as one or more packs of cigarettes a day; heavy drinking was defined as more than two drinks per day. The researchers also grouped participants according to whether they carried the apolipoprotein E-4 [ApoE-4] gene variant, which increases risk for Alzheimer's disease.
The study showed:
  • Heavy drinkers developed the disease 4.8 years before those who did not drink as much.
  • Alzheimer's developed 2.3 years earlier in heavy smokers than in those who were not heavy smokers.
  • The gene variant reduced the age of onset by three years.
  • People with all three risk factors developed Alzheimer's 8.5 years earlier than those who had no risk factors.
Alzheimer's disease is a progressive, incurable brain disease that leads to the loss of mental abilities that affect memory and learning. According to the Alzheimer's Association, about 5 million people in the U.S. live with the condition. However, there are concerns that the number will skyrocket in the near future as America's baby boomers reach their golden years.


Reference: Ranjan Duara, MD, Web MD


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Is the Founder of Fitness Builders 4 Life,the WorkOut GEM,G350,G180, G90, Eat 4 Life, Clean, Lean & Mean & Ask Glen. The mission of the Fitness Builders is to provide the community with health education and to empower people to change unhealthy lifestyles thereby increasing life expectancy. By educating the community on healthier lifestyle practices it is the intent of Fitness Builders to reduce the ravages of obesity, heart disease, cancer and other lifestyle or self inflicted diseases. Glen is also a AMA Certified Nutrition Specialist and a ACE, ACSM, NASM Certified Personal Trainer has 30+ years in Sports, Exercise Science and Nutritional Food Management, Learning and Mentoring Men and Women on a more Mental & Physical Healthy Life Style consisting of a low fat, low salt, Low carbohydrate, high protein, organic nutrition which also includes moderate exercise and mental awareness. Stay Informed, Live long and be Mentally and Physically Healthy! Any questions? Ask Glen!

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